Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.30, sa.6, ss.162-166, 2002 (Scopus)
The aim of the present study was to compare the clinical effects of 25 μg (0.5 mL) fentanyl combined with 1.5 mL % 0.5 hyperbaric bupivacaine and 2 mL % 0.5 hyperbaric bupivacaine, in patients undergoing transurethral resection. Fourty patients, scheduled for transurethral resection of the prostate or bladder tumors were randomly assigned into two groups. Spinal anaesthesia was performed with 7.5 mg hyperbaric bupivacaine+25 μg fentanyl in Group II (n=20), 10 mg hyperbaric bupivacaine in Group II (n-20). Systolic arterial pressure (SAP), diastolic arterial pressure (DAP), heart rate, peripheral oxygen saturation (SpO2), duration and the degree of motor and sensorial blocks and analgesic efficacy were recorded perioperatively. Although there were no significant differences between two groups regarding hemodynamic parameters, we observed bradicardia in four patients in Group II. Comparison of pre and post blockade values of SpO2 showed 5 % decrease in two patients in Group I. While the duration of the sensorial block was longer in Group I, intensity of motor block was higher in Group II (p<0.05). Group I patients required postoperative analgesia less than Group II within the first 24 hours (p<0.05). While shivering was observed in seven patients in Group II, it was not observed in Group I (p<0.05). We conclude that in transurethral resection both procedures provided adequate analgesia and anaesthesia, but the potential risk of respiratory depression must always be considered in patients for whom fentanyl administration will be considered.