The aims of this study were to compare some laboratory parameters found in puppies with carpal laxity syndrome (Group I, n = 12) and in healthy controls of the same age (Group II, n = 10) and to determine the effectiveness of bandage application as treatment. The affected puppies presented bilateral flexion and/or extension (n = 7) or unilateral deformity (n = 5) which were not associated with radiographic signs. No significant difference for haematological parameters and for plasma Ca and P concentrations was evidenced between the 2 groups but the plasma ALP (alkaline phosphatase) activity was markedly increased in the diseased group, suggesting an intense osteoblast activity. The application of polyvinyl chloride (PVC) bandage renewed at 10-day interval has greatly alleviated the joint deformity within 15 clays for 75% of puppies and within 45 days for 100% of them. These results suggest that bone formation could be partially altered during the carpal laxity syndrome in dog and that bandage would promote an adequate osteogenesis.