Quantitative Susceptibility Mapping in Identification of Intracranial Hemorrhage: A Case Report


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Dundar M. S. , Koç G. , Gümüş K. Z. , Caner Y.

International Biomedical Engineering Congress 2015, Lefkoşa, Cyprus (Kktc), 12 - 14 March 2015, pp.66

  • Publication Type: Conference Paper / Summary Text
  • City: Lefkoşa
  • Country: Cyprus (Kktc)
  • Page Numbers: pp.66

Abstract

Differentiation of intracranial hemorrhage and calcification on conventional MR images is often challenging. Both pathologies show varying signal intensities on T1- and T2-weighted images. Phase images obtained in Susceptibility Weighted Imaging[1] and Quantitative Susceptibility Mapping[2] were utilized in identification of hemorrhage and calcification. This study explores the benefits of QSM on a case with hemorrhages and compare its findings with SWI phase images.   

QSM provides a map of tissue magnetic susceptibility. The voxel intensity in QSM is linearly proportional to the underlying tissue apparent magnetic susceptibility, which is useful for chemical identification and quantification of specific biomarkers including iron and calcium[2].

Case: MR images of 10-year-old patient with diagnosis of hemorrhage and microhemorrhages were analyzed. Images consisted of conventional MRI, SWI and multi-echo gradient echo (GE) sequence. QSM images were reconstructed from multi-echo GE images[3]. Both QSM images and SWI phase images were found successful in identifying microhemorrhages. The hemorrhage was observed to have heterogeneous appearance on SWI in contrast to QSM. The comparative results of SWI and QSM will be discussed in the poster.