Simultaneous use of phenylboronic acid as a phase transfer agent and targeting ligand for gold nanoparticles

Karaagac Z., Onal I., Ildız N., Öçsoy İ.

MATERIALS LETTERS, cilt.280, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 280
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.matlet.2020.128561
  • Dergi Adı: MATERIALS LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chimica, Communication Abstracts, Compendex, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: Nanoparticles, Functional, Colloidal processing, Phase transformation
  • Erciyes Üniversitesi Adresli: Evet

Özet

Herein, we have rationally utilized 4-mercaptophenylboronic acid (4-MPBA) as a hydrophilic ligand for phase transfer of gold (Au) NPs from non-hydrolytic system into aqueous solutions and as a targeting ligand for recognition of model pathogen. In principle, while free thiol end of 4-MPBA conjugates to surface of hydrophobic Au NPs to form stable Au NP in aqueous solutions, diol groups can bind to glycan on the membrane of pathogens through cis-diol configuration. Finally, this ligand can be applied to other hydrophobic metallic and metel oxide NPs for phase transfer and molecular recognition. (C) 2020 Elsevier B.V. All rights reserved.