In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid beta-peptide-induced toxicity and inhibition of GSK-3 beta, CK-1 delta, and BACE-1 enzymes relevant to Alzheimer's disease

GÜRBÜZ, PERİHAN; DOKUMACI, Alim; GÜNDÜZ, MİYASE; Perez, Concepcion; GÖGER, FATİH; Paksoy, Mehmet; Yerer, MÜKERREM; DEMİREZER, LÜTFİYE

doi:10.1016/j.jsps.2021.01.007

In vitro biological activity of Salvia fruticosa Mill. infusion against amyloid beta-peptide-induced toxicity and inhibition of GSK-3 beta, CK-1 delta, and BACE-1 enzymes relevant to Alzheimer's disease

GÜRBÜZ P., DOKUMACI A. H., GÜNDÜZ M. G., Perez C., GÖGER F., Paksoy M. Y., ...Daha Fazla

SAUDI PHARMACEUTICAL JOURNAL, cilt.29, sa.3, ss.236-243, 2021 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 29 Sayı: 3
Basım Tarihi: 2021
Doi Numarası: 10.1016/j.jsps.2021.01.007
Dergi Adı: SAUDI PHARMACEUTICAL JOURNAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, International Pharmaceutical Abstracts, Directory of Open Access Journals
Sayfa Sayıları: ss.236-243
Anahtar Kelimeler: Lamiaceae, Neurotoxicity, Molecular modeling, Neuroprotection, Rosmarinic acid
Erciyes Üniversitesi Adresli: Evet

Özet

Salvia species have been traditionally used to improve cognition and have been proved to be a potential natural treatment for Alzheimer's disease. Salvia fruticosa Mill. (Turkish sage or Greek sage) demonstrated to have anticholinergic effects in vitro.