Effect of granulocyte colony-stimulating factor in experimental methicillin resistant Staphylococcus aureus sepsis

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ALP E., GOZUKUCUK S., CANOZ O., KIRMACI B., Doganay M.

BMC INFECTIOUS DISEASES, cilt.4, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1186/1471-2334-4-43
  • Dergi Adı: BMC INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: Methicillin resistant Staphylococcus aureus (MRSA) is the leading pathogenic cause of nosocomial infections, especially in bacteraemia and sepsis. The essential therapy for MRSA infection is glycopeptides. Therapeutic failure can be seen with this therapy and the mortality is still high. The aim of this study was to evaluate the additional effect of G-CSF on the traditional antibiotic treatment in an experimental MRSA sepsis.