Relationship between renal tubulointerstitial fibrosis and serum prolidase enzyme activity


ESER B., DOĞAN İ., Komut E., KOYUNCU S. , Aydemir N., Colak A., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.45, ss.567-573, 2020 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 45 Konu: 5
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/tjb-2020-0026
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Sayfa Sayıları: ss.567-573

Özet

Objectives: The severity of interstitial fibrosis/tubular atrophy (IFTA) is the most important determinant of the irreversible progression of chronic kidney disease (CKD). Prolidase is the key enzyme in collagen turnover and is associated with an extracellular matrix increase. We aimed to evaluate the relationship between the presence and degree of IFTA and serum prolidase enzyme activity (SPEA) in patients undergoing a renal biopsy.