Protein oxidation status in patients with ankylosing spondylitis

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Yazici C., Kose K., Calis M., Kuzuguden S., Kirnap M.

RHEUMATOLOGY, cilt.43, sa.10, ss.1235-1239, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 10
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1093/rheumatology/keh317
  • Dergi Adı: RHEUMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1235-1239
  • Anahtar Kelimeler: advanced oxidation protein products, ankylosing spondylitis, myeloperoxidase, neutrophil activation, protein oxidation, CHRONIC-RENAL-FAILURE, LIPID-PEROXIDATION, DISEASE-ACTIVITY, WHOLE-BLOOD, NEUTROPHILS, PRODUCTS, STRESS, INFLAMMATION, ANTIOXIDANTS, METABOLISM
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objectives. Ankylosing spondylitis (AS) is a chronic inflammatory disease with unknown aetiology. Since various functions of neutrophils are increased in AS, neutrophil activation-mediated oxidative stress may have an important role in the pathogenesis of AS. Therefore, the importance of neutrophil activation as the main source of oxidative stress was investigated in patients with AS.