Protein oxidation status in patients with ankylosing spondylitis

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Yazici C., Kose K., Calis M., Kuzuguden S., Kirnap M.

RHEUMATOLOGY, vol.43, no.10, pp.1235-1239, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 10
  • Publication Date: 2004
  • Doi Number: 10.1093/rheumatology/keh317
  • Journal Name: RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1235-1239
  • Keywords: advanced oxidation protein products, ankylosing spondylitis, myeloperoxidase, neutrophil activation, protein oxidation, CHRONIC-RENAL-FAILURE, LIPID-PEROXIDATION, DISEASE-ACTIVITY, WHOLE-BLOOD, NEUTROPHILS, PRODUCTS, STRESS, INFLAMMATION, ANTIOXIDANTS, METABOLISM
  • Erciyes University Affiliated: Yes

Abstract

Objectives. Ankylosing spondylitis (AS) is a chronic inflammatory disease with unknown aetiology. Since various functions of neutrophils are increased in AS, neutrophil activation-mediated oxidative stress may have an important role in the pathogenesis of AS. Therefore, the importance of neutrophil activation as the main source of oxidative stress was investigated in patients with AS.