Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis

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Copy For Citation

Kose K., Utaş S., Yazici C., Akdas A., Kelestimur F.

BRITISH JOURNAL OF DERMATOLOGY, vol.144, no.6, pp.1121-1126, 2001 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 144 Issue: 6
• Publication Date: 2001
• Doi Number: 10.1046/j.1365-2133.2001.04221.x
• Journal Name: BRITISH JOURNAL OF DERMATOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1121-1126
• Erciyes University Affiliated: Yes

Abstract

Background T-cell activation has been implicated in the pathogenesis of psoriasis; adenosine deaminase (ADA) activity has been considered as a marker of T-cell activation. The antithyroid drug propylthiouracil (PTU) has recently been shown to have beneficial effects on psoriatic lesions, probably by acting on the immune system.