Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis


Kose K. , Utaş S. , Yazici C. , Akdas A. , Kelestimur F.

BRITISH JOURNAL OF DERMATOLOGY, cilt.144, sa.6, ss.1121-1126, 2001 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 144 Konu: 6
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1046/j.1365-2133.2001.04221.x
  • Dergi Adı: BRITISH JOURNAL OF DERMATOLOGY
  • Sayfa Sayıları: ss.1121-1126

Özet

Background T-cell activation has been implicated in the pathogenesis of psoriasis; adenosine deaminase (ADA) activity has been considered as a marker of T-cell activation. The antithyroid drug propylthiouracil (PTU) has recently been shown to have beneficial effects on psoriatic lesions, probably by acting on the immune system.