Effect of propylthiouracil on adenosine deaminase activity and thyroid function in patients with psoriasis

Kose K., Utaş S., Yazici C., Akdas A., Kelestimur F.

BRITISH JOURNAL OF DERMATOLOGY, cilt.144, sa.6, ss.1121-1126, 2001 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 144 Sayı: 6
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1046/j.1365-2133.2001.04221.x
  • Dergi Adı: BRITISH JOURNAL OF DERMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1121-1126
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background T-cell activation has been implicated in the pathogenesis of psoriasis; adenosine deaminase (ADA) activity has been considered as a marker of T-cell activation. The antithyroid drug propylthiouracil (PTU) has recently been shown to have beneficial effects on psoriatic lesions, probably by acting on the immune system.