In this paper, epilepsy diagnosis has been investigated by using Electroencephalogram (EEG) records. For this purpose, a technique as the classifier Artificial Neural Networks (ANN), which is frequently used and known as an active classification technique, is used. Particle Swarm Optimization (PSO) method is preferred as training algorithm for ANN. PSO based neural network model (PSONN) is diversified according to PSO variants and seven PSO based neural network models are described. In these models, PSONN3 and PSONN4 are determined as appropriate models for the classification. In addition, different number of neurons, iterations/generations and swarm sizes have been considered and tried. Obtained results of the models have been evaluated.