Encapsulation of Flurbiprofen by Chitosan Using a Spray-Drying Method with In Vitro Drug Releasing and Molecular Docking

Akyuz L., Duman F., Kaya M.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.1, ss.34-39, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.95867
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.34-39
  • Anahtar Kelimeler: Biodegradable, drug delivery, molecular docking, characterization, DELIVERY-SYSTEM, NANOPARTICLES, FORMULATION
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objectives: This study aimed to prepare chitosan-flurbiprofen micro-nano spheres as environmentally friendly for drug releasing by spray-drying method without any cross-linking agent. It was also aimed to reveal the favorable binding geometries of chitosan and flurbiprofen using molecular modeling.