Encapsulation of Flurbiprofen by Chitosan Using a Spray-Drying Method with In Vitro Drug Releasing and Molecular Docking
TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.1, ss.34-39, 2017 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 1
- Basım Tarihi: 2017
- Doi Numarası: 10.4274/tjps.95867
- Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.34-39
- Anahtar Kelimeler: Biodegradable, drug delivery, molecular docking, characterization
- Erciyes Üniversitesi Adresli: Evet
Özet
Objectives: This study aimed to prepare chitosan-flurbiprofen micro-nano spheres as environmentally friendly for drug releasing by spray-drying method without any cross-linking agent. It was also aimed to reveal the favorable binding geometries of chitosan and flurbiprofen using molecular modeling.