Congenital alacrima in a patient with G (Opitz frias) syndrome

Dundar M., Erkilic K., Demiryılmaz F., Kucukaydin M., Kendirci M., Okur H., ...More

HUMAN GENETICS, vol.97, no.4, pp.540-542, 1996 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 97 Issue: 4
  • Publication Date: 1996
  • Doi Number: 10.1007/bf02267083
  • Journal Name: HUMAN GENETICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.540-542
  • Erciyes University Affiliated: Yes


Congenital alacrima is an autosomal dominant disorder showing markedly deficient lacrimation and punctate corneal epithelial erosions. The G (Opitz-Frias) syndrome is also an autosomal dominant disorder characterised by hypertelorism, hypospadias, strider, and dysphagia. Here we report a 5-year-old boy with the G syndrome presenting congenital alacrima.