Can a glucagon stimulation test characterized by lower GH cut-off value be used for the diagnosis of growth hormone deficiency in adults?

Diri, Halit; KARACA, ZÜLEYHA; Simsek, Yasin; TANRIVERDİ, Fatih; ÜNLÜHİZARCI, KÜRŞAD; SELÇUKLU, AHMET; KELESTIMUR, Fahrettin

doi:10.1007/s11102-015-0666-1

Can a glucagon stimulation test characterized by lower GH cut-off value be used for the diagnosis of growth hormone deficiency in adults?

Diri H., KARACA Z. C., Simsek Y., TANRIVERDİ F., ÜNLÜHİZARCI K., SELÇUKLU A., ...Daha Fazla

PITUITARY, cilt.18, sa.6, ss.884-892, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 18 Sayı: 6
Basım Tarihi: 2015
Doi Numarası: 10.1007/s11102-015-0666-1
Dergi Adı: PITUITARY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.884-892
Anahtar Kelimeler: Growth hormone deficiency, IGF-I, Glucagon stimulation test, Insulin tolerance test
Erciyes Üniversitesi Adresli: Evet

Özet

Objective The aim of this study was to assess diagnostic values of insulin tolerance test (ITT), glucagon stimulation test (GST), and insulin like growth factor-I (IGF-I) level, to find optimal GH cut-off values for GST, and to evaluate efficiencies of patient age, gender, body-mass index (BMI), and additional pituitary hormone deficiencies (PHDs) in the diagnosis of growth hormone deficiency (GHD).