Can a glucagon stimulation test characterized by lower GH cut-off value be used for the diagnosis of growth hormone deficiency in adults?

Diri H., KARACA Z. C., Simsek Y., TANRIVERDİ F., ÜNLÜHİZARCI K., SELÇUKLU A., ...More

PITUITARY, vol.18, no.6, pp.884-892, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1007/s11102-015-0666-1
  • Journal Name: PITUITARY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.884-892
  • Keywords: Growth hormone deficiency, IGF-I, Glucagon stimulation test, Insulin tolerance test, INSULIN TOLERANCE-TEST, (GH)-RELEASING HORMONE, PITUITARY SURGERY, PROVOCATIVE TESTS, SECRETION, ARGININE, HYPOGLYCEMIA, HYPOPITUITARISM, RESPONSES, CORTISOL
  • Erciyes University Affiliated: Yes

Abstract

Objective The aim of this study was to assess diagnostic values of insulin tolerance test (ITT), glucagon stimulation test (GST), and insulin like growth factor-I (IGF-I) level, to find optimal GH cut-off values for GST, and to evaluate efficiencies of patient age, gender, body-mass index (BMI), and additional pituitary hormone deficiencies (PHDs) in the diagnosis of growth hormone deficiency (GHD).