A family with two different chromosomal translocations

Ozkul Y., Dundar M.

ANNALES DE GENETIQUE, cilt.45, sa.4, ss.185-187, 2002 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 4
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1016/s0003-3995(02)01145-0
  • Dergi Adı: ANNALES DE GENETIQUE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.185-187
  • Erciyes Üniversitesi Adresli: Evet

Özet

The proband was a 22-year-old woman who had two spontaneous abortions in the first trimester of pregnancy. She had a consanguineous marriage with no history of malformation or developmental disorders in the family. Her gynecological examination was normal. Chromosome analysis of the family showed two different katyotypes 46,XYt(1;16)(p22;p13) and 46,XX,t(1;16)(q24;q24) using high-resolution banding (HRB). Proband's family was also examined for chromosome analysis. A t(1;16)(p22;p13) was found in the husband's father and other relatives, and a t(1;16)(q24;q24) translocation in the proband's family. This second tanslocation is not found in her parents. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.