Protective effects of curcumin and beta-carotene on cisplatin-induced cardiotoxicity: An experimental rat model

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Bahadir A., Ceyhan A., Gergın O. O. , Yalçın B. , Ülger M. , Özyazgan T. M. , et al.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.19, ss.213-221, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Objective: Cisplatin (CDDP) has been known to be an effective antineoplastic drug; however, it has a cardiotoxic effect. Curcumin (CMN) and beta-carotene (BC) have been suggested to protect biological systems against CDDP-induced damage. The current study was conducted to evaluate the possible protective roles of CMN and BC on CDDP-induced cardiotoxicity in rat cardiac tissues.