Health sciences quarterly (Online), cilt.5, sa.3, ss.381-388, 2025 (TRDizin)
Sepsis is a life-threatening condition characterized by a dysregulated host response to infection, leading to organ
dysfunction. Early recognition and timely intervention are critical in reducing mortality. This study aimed to assess
the knowledge levels of healthcare professionals and students regarding sepsis and highlight the importance
of early diagnosis and management. A multicenter cross-sectional survey was conducted among healthcare
professionals working in the emergency department of a university hospital and paramedic students undergoing
internships. The questionnaire assessed participants’ knowledge of sepsis criteria, early warning signs, and
management strategies. Statistical analyses were performed using appropriate tests, with a significance level of
p<0.05. A total of 250 participants completed the survey. While 95% recognized sepsis as a medical emergency, only
52% were familiar with the Sepsis-3 diagnostic criteria. Knowledge of Sequential Organ Failure Assessment (SOFA)
and Quick Sequential Organ Failure Assessment (qSOFA) scoring systems was highest among physicians (90.6%)
but significantly lower among paramedic students (3.4% and 1.7%, respectively) (p=0.000). Additionally, 58% of
participants identified crystalloid therapy as necessary in hypotensive sepsis patients. The study revealed that 55%
of participants had not received sepsis training in the past year, with non-physician healthcare workers showing the
lowest awareness levels. This study highlights gaps in sepsis knowledge among healthcare professionals, particularly
among frontline non-physician staff. Targeted educational programs incorporating theoretical understanding and
practical simulations are essential for improving early recognition and management of sepsis. Enhancing sepsis
awareness and adherence to guidelines can significantly reduce mortality rates.
Keywords: Sepsis, knowledge assessment, healthcare professionals, early recognition, Sepsis-3 criteria