Real data-based optimal control strategies for assessing the impact of the Omicron variant on heart attacks

EVİRGEN F., ÖZKÖSE F., Yavuz M., ÖZDEMİR N.

AIMS BIOENGINEERING, sa.3, ss.218-239, 2023 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2023
  • Doi Numarası: 10.3934/bioeng.2023015
  • Dergi Adı: AIMS BIOENGINEERING
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.218-239
  • Erciyes Üniversitesi Adresli: Evet

Özet

This paper presents an investigation into the relationship between heart attacks and the Omicron variant, employing a novel mathematical model. The model incorporates two adjustable control parameters to manage the number of infected individuals and individuals with the Omicron variant. The study examines the model's positivity and boundedness, evaluates the reproduction number (R0), and conducts a sensitivity analysis of the control parameters based on the reproduction number. The model's parameters are estimated using the widely utilized least squares curve fitting method, employing real COVID-19 cases from Tu & BULL;rkiye. Finally, numerical simulations demonstrate the efficacy of the suggested controls in reducing the number of infected individuals and the Omicron population.