Magnesium Levels in Children with Chronic Kidney Disease Stages 1-3

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YILMAZ K., DURSUN İ., DÜŞÜNSEL R., GÜNDÜZ Z., YEL S.

REVISTA DE NEFROLOGIA, DIALISIS Y TRANSPLANTE, cilt.41, sa.1, ss.36-41, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 1
  • Basım Tarihi: 2021
  • Dergi Adı: REVISTA DE NEFROLOGIA, DIALISIS Y TRANSPLANTE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals, DIALNET
  • Sayfa Sayıları: ss.36-41
  • Anahtar Kelimeler: magnesium, chronic kidney disease stages 1-3, children, homeostasis
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objective: The objective of this study was to assess serum and urinary magnesium levels in children who have chronic kidney disease stages 1-3. Methods: Eighty-seven patients who were followed at pediatric nephrology department for chronic kidney disease were included in the study. Age, gender, magnesium, dietary magnesium, and creatinine levels, and fractionated magnesium excretion for all cases were recorded. Patients with chronic kidney disease and control groups were compared in terms of these data. Results: Thirty-nine cases with chronic kidney disease were stage 1, 26 were stage 2, and 22 were stage 3. Average age was 9.9 ± 2.8 years in the control group and 10.2 ± 2.6 years in the chronic kidney disease group. The serum magnesium levels were significantly higher in the stage 3 group than in the control group (P<0.001). Also, in stage 3, fractionated magnesium excretion levels were higher compared to the control group (P<0.001). Conclusion: In chronic kidney disease with advancing renal failure, hypermagnesemia is frequently seen. Serum magnesium levels should be measured periodically in all the children with chronic kidney disease stage 3 to investigate magnesium abnormalities and assess clinical results.