Akademik Veri Yönetim Sistemi
BEILSTEIN JOURNAL OF NANOTECHNOLOGY, cilt.16, ss.1246-1276, 2025 (SCI-Expanded, Scopus)
The emergence of nanotechnology offers a promising avenue for enhancing cancer treatment outcomes. In this context, biomimeticnanoparticles have emerged as an exciting frontier in the field of biomedicine. These nanoparticles can emulate essential biologicalfunctions, drawing from an abundant reservoir of cellular capabilities. This includes engaging in biological binding, precise homingto tumor sites, and interaction with immune cells. These inherent traits endow biomimetic nanoparticles with a suite of intelligentfeatures, including biocompatibility, low immunogenicity, reduced toxicity, immune evasion, prolonged circulation, homotypicbinding, enhanced tumor targeting, and the capability of precise delivery. By integrating biologically inspired coatings derived fromcell membranes with nanoparticle cores, these carriers become highly versatile vessels for encapsulating a wide array of thera-peutic agents. As a result, they are being extensively harnessed for the precise delivery of drugs and genes, underpinning numerousbiomedical applications. This discussion delves into the challenges and opportunities presented by biomimetic nanoparticles and offers a comprehensive exploration of their fundamentals and recent breakthroughs, with an eye towards clinical translation. Bybridging the gap between scientific innovation and clinical utility, biomimetic nanoparticles hold great promise for advancing thefield of cancer treatment.