Serum micro-rna profiles in patients with autosomal dominant polycystic kidney disease according to hypertension and renal function

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KOÇYİĞİT I., TAHERİ S., ŞENER E. F., EROĞLU E., Ozturk F., ÜNAL A., ...More

BMC NEPHROLOGY, vol.18, 2017 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2017
  • Doi Number: 10.1186/s12882-017-0600-z
  • Journal Name: BMC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Erciyes University Affiliated: Yes

Abstract

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder with unclear disease mechanism. Currently, overt hypertension and increased renal volume are the best predictors of renal function. In this study, we assessed the usefulness of selected circulating microRNAs (miRs) to predict disease progress in a cohort with ADPKD.