Effects of azithromycin on cyclosporine-induced gingival hyperplasia in renal transplant patients

Tokgoz B., SARI H. I., Yildiz O., ASLAN S., Sipahioglu M. H., Okten T., ...Daha Fazla

TRANSPLANTATION PROCEEDINGS, cilt.36, sa.9, ss.2699-2702, 2004 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 9
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.transproceed.2004.09.059
  • Dergi Adı: TRANSPLANTATION PROCEEDINGS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2699-2702
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background. Gingival hyperplasia is a well-known complication of cyclosporine therapy, affecting 21% to 35% of renal transplant patients. Metronidazole, clarithromycin, and azithromycin, all azalid antimicrobial agents derived from the macrolide antibiotic erythromycin, have been used for treatment. Marked improvements in gingival hyperplasia have been recorded in particular with azithromycin. The aim of the present study was to investigate histopathological features of cyclosporine-induced gingival hyperplasia and to evaluate the quantitative efficacy of short-term azithromycin therapy.