Intravenous N-acetylcysteine plus high-dose hydration versus high-dose hydration and standard hydration for the prevention of contrast-induced nephropathy: CASIS-A multicenter prospective controlled trial

Koc, Fatih; Ozdemir, Kurtulus; Kaya, Mehmet; Dogdu, Orhan; Vatankulu, Mehmet; Ayhan, Selim; Erkorkmaz, Unal; Sonmez, Osman; Aygul, Meryem; KALAY, NİHAT; Kayrak, Mehmet; Karabag, Turgut; Alihanoglu, Yusuf; Gunebakmaz, Özgür

doi:10.1016/j.ijcard.2010.10.041

Intravenous N-acetylcysteine plus high-dose hydration versus high-dose hydration and standard hydration for the prevention of contrast-induced nephropathy: CASIS-A multicenter prospective controlled trial

Koc F., Ozdemir K., Kaya M. G., Dogdu O., Vatankulu M. A., Ayhan S., ...Daha Fazla

INTERNATIONAL JOURNAL OF CARDIOLOGY, cilt.155, sa.3, ss.418-423, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 155 Sayı: 3
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.ijcard.2010.10.041
Dergi Adı: INTERNATIONAL JOURNAL OF CARDIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.418-423
Erciyes Üniversitesi Adresli: Evet

Özet

Background: Contrast-induced nephropathy (CIN) is a leading cause of acute renal failure and affects mortality and morbidity. We investigated the efficacy of prophylactic intravenous (IV) N-acetylcysteine (NAC) and hydration for the prevention of CIN in patients with mild to moderate renal dysfunction who are undergoing coronary angiography and/or percutaneous coronary intervention (PCI).