Intravenous N-acetylcysteine plus high-dose hydration versus high-dose hydration and standard hydration for the prevention of contrast-induced nephropathy: CASIS-A multicenter prospective controlled trial


Koc F., Ozdemir K., Kaya M. G. , Dogdu O. , Vatankulu M. A. , Ayhan S., ...Daha Fazla

INTERNATIONAL JOURNAL OF CARDIOLOGY, cilt.155, ss.418-423, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 155 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.ijcard.2010.10.041
  • Dergi Adı: INTERNATIONAL JOURNAL OF CARDIOLOGY
  • Sayfa Sayıları: ss.418-423

Özet

Background: Contrast-induced nephropathy (CIN) is a leading cause of acute renal failure and affects mortality and morbidity. We investigated the efficacy of prophylactic intravenous (IV) N-acetylcysteine (NAC) and hydration for the prevention of CIN in patients with mild to moderate renal dysfunction who are undergoing coronary angiography and/or percutaneous coronary intervention (PCI).