Potential anti-Alzheimer effects of selected Lamiaceae plants through polypharmacology on glycogen synthase kinase-3 beta, beta-secretase, and casein kinase 1 delta

Gürbüz P., Martinez A., Perez C., Martinez-Gonzalez L., Goger F., Ayran I.

INDUSTRIAL CROPS AND PRODUCTS, cilt.138, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 138
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.indcrop.2019.05.080
  • Dergi Adı: INDUSTRIAL CROPS AND PRODUCTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Amyloid beta, Lamiaceae, GSK-3 beta, Alzheimer's disease, Origanum onites, LC-DAD-ESI-MS/MS, ROSMARINUS-OFFICINALIS L., INDUCED NEUROTOXICITY, SALVIA-MILTIORRHIZA, PHENOLIC-COMPOUNDS, FIBRIL FORMATION, ESSENTIAL OILS, 1 DELTA, ACETYLCHOLINESTERASE, INHIBITION, EXTRACT
  • Erciyes Üniversitesi Adresli: Evet

Özet

The aerial parts of Lamiaceae plants have been used since ancient times all over the world, especially in Mediterranean cultures, for their medicinal and culinary properties. Although some of them have a historical role in the improvement of cognition and memory, the precise mechanism of these plants remains unclear.