Changes in MAP-2 and GFAP immunoreactivity in pup hippocampus during prepubertal and pubertal periods caused by maternal subclinical hypothyroidism


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Yildirim A. B. , Ozdamar S., Yalçın B. , Karabulut D.

EUROPEAN JOURNAL OF ANATOMY, vol.23, pp.27-40, 2019 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 23
  • Publication Date: 2019
  • Title of Journal : EUROPEAN JOURNAL OF ANATOMY
  • Page Numbers: pp.27-40

Abstract

An absence of the thyroid hormone during the critical period of brain development causes delayed maturation of glial cells and neurons and decreases the number of hippocampal cells. This study aims to examine the impact of maternal subclinical hypothyroidism (SCH) on pup hippocampus during the prepubertal and pubertal periods by means of assessing the histopathological changes in astrocytes and neurons.