BioVar: an online biological variation analysis tool

KORKMAZ S., Zarasiz G., Goksuluk D., Senes M., Sonmez C., Yucel D.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.45, no.5, pp.479-489, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 5
  • Publication Date: 2020
  • Doi Number: 10.1515/tjb-2019-0437
  • Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.479-489
  • Keywords: Biological variation, Laboratory tests, Nested ANOVA, Variance components, Web tool
  • Erciyes University Affiliated: Yes

Abstract

Objectives: Biological variation (BV) analysis of laboratory tests gets increased attention due to its practical applications. These applications include correct interpretation of laboratory tests, the decision on the availability of reference intervals, contributions to clinical decision-making. It is critical to derive the BV information accurately and reliably. Another crucial step is to perform the statistical analysis of the BV data. Although there are updated and comprehensive guidelines, there is no reliable and comprehensive tool to perform statistical analysis of BV data.