Endothelial Progenitor Cells and NADPH Oxidase Enzyme Activity in the Development of an Aortic Aneurysm.

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Bingol B., Elcik D., Kutuk S., Özsoy S., Kelesoglu Ş., Tuncay A., ...More

Brazilian journal of cardiovascular surgery, vol.37, no.4, pp.501-510, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 4
  • Publication Date: 2022
  • Doi Number: 10.21470/1678-9741-2020-0458
  • Journal Name: Brazilian journal of cardiovascular surgery
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Page Numbers: pp.501-510
  • Keywords: Thoracic Aortic Aneurysms, Dihydrorhodamine 123, Endothelial Progenitor Cells, Flow Cytometry, Disease Progression
  • Erciyes University Affiliated: Yes

Abstract

Introduction: Endothelial progenitor cells (EPCs) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme activity may affect the vessel wall and have a role in development of aortic aneurysms. EPCs originate from hematopoietic stem cells and can be enumerated from peripheral blood samples by flow cytometry. In this study, we aimed to evaluate the relation of EPC number and NADPH oxidase enzyme activity in the development of thoracic aortic aneurysm (TAA).