Vortioxetine suppresses epileptiform activity and cognition deficits in a chronic PTZ-induced kindling rat model

Taskiran M., Unal G.

EPILEPTIC DISORDERS, cilt.23, sa.6, ss.893-900, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 6
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1684/epd.2021.1344
  • Dergi Adı: EPILEPTIC DISORDERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.893-900
  • Anahtar Kelimeler: vortioxetine, SSRI, PTZ-induced epilepsy, seizure, NOR, DOUBLE-BLIND, FLUOXETINE, SEROTONIN, EPILEPSY, SEIZURES, SCHIZOPHRENIA, PLACEBO
  • Erciyes Üniversitesi Adresli: Evet

Özet

Objective. This study aimed to examine the effects of vortioxetine, a novel antidepressant, on epileptiform activity in pentylenetetrazole (PTZ)-induced kindling model in rats.