The effects of treatment with drospirenone/ethinyl oestradiol alone or in combination with metformin on elastic properties of aorta in women with polycystic ovary syndrome


KAYA M., Calapkorur B. , Karaca Z. C. , Yildirim S. , Celik A. , Akpek M. , ...Daha Fazla

CLINICAL ENDOCRINOLOGY, cilt.77, ss.885-892, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 77 Konu: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1111/j.1365-2265.2012.04436.x
  • Dergi Adı: CLINICAL ENDOCRINOLOGY
  • Sayfa Sayıları: ss.885-892

Özet

Background Polycystic ovary syndrome (PCOS) is a heterogeneous clinical condition. Oral contraceptive pills (OCPs) have conventionally been the mainstay of treatment for the amelioration of hyperandrogenism and regulation of menstrual cycles in women with PCOS. Metformin has beneficial effects on insulin resistance and endothelial functions. To our knowledge, the effect of metformin/OCP combination treatment on aortic stiffness has not been studied so far.