The effects of treatment with drospirenone/ethinyl oestradiol alone or in combination with metformin on elastic properties of aorta in women with polycystic ovary syndrome

KAYA M., Calapkorur B. , Karaca Z. C. , Yildirim S. , Celik A. , Akpek M. , ...More

CLINICAL ENDOCRINOLOGY, vol.77, no.6, pp.885-892, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1111/j.1365-2265.2012.04436.x
  • Page Numbers: pp.885-892


Background Polycystic ovary syndrome (PCOS) is a heterogeneous clinical condition. Oral contraceptive pills (OCPs) have conventionally been the mainstay of treatment for the amelioration of hyperandrogenism and regulation of menstrual cycles in women with PCOS. Metformin has beneficial effects on insulin resistance and endothelial functions. To our knowledge, the effect of metformin/OCP combination treatment on aortic stiffness has not been studied so far.