SYNTHESIS AND REACTIONS OF SOME 1H-PYRAZOLE-3 CARBOXYLIC ACID CHLORIDE


İLHAN I. Ö. , ZUHAL S., Onal Z., SARIPINAR E.

HETEROCYCLIC COMMUNICATIONS, vol.15, no.4, pp.279-284, 2009 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2009
  • Doi Number: 10.1515/hc.2009.15.4.279
  • Title of Journal : HETEROCYCLIC COMMUNICATIONS
  • Page Numbers: pp.279-284

Abstract

The pyrazole-carboxylic acid chloride 2 was obtained from the reaction of 4-Benzoyl-1-(2,4-dinitrophenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid I and thionyl chloride. 1H-Pyrazole-3 carboxylic acid chlorides 2 can easily be converted into corresponding 1H-pyrazole-3-carboxylic acid amide derivatives 4 and 1H-pyrazole-3-carboxamide derivatives 6 from the reaction with various aliphatic and aromatic amines. The structures of these new synthesized compounds were determined from the IR,(1)H and (13)C NMR spectroscopic data and elemental anaylsis.