Akademik Veri Yönetim Sistemi
Erciyes Tip Dergisi, cilt.26, sa.3, ss.113-118, 2004 (Scopus)
Purpose: To determine the electroretinographic responses in patients with Bietti's crystalline dystrophy and to compare them with normal values. Materials-Methods: After a complete ophthalmologic examination, fundus fluorescein angiography (FFA), visual field examination and electrophysiological tests were performed in 11 patients with Bietti's crystalline dystrophy. Visual field examination was performed with Goldmann perimeter and electrophysiological examination with full-field electroretinogram (ERG). ERG values of these patients were compared with normal values of age-and sex matched 15 individuals. Results: There were diffuse or focal pigment epithelial atrophies determined by FFA in all patients with Bietti's crystalline dystrophy. Visual field examination revealed various defects except in two cases. Mean b-wave amplitudes of rod response, maximal combined response and cone response of ERG were 79.1±35.0 mV, 163.0±76.0 mV, and 69.0±27.0 mV, respectively. The values of these parameters in normal individuals were 114.8±38.7 mV, 231.1±26.4 mV and 88.0±13.9 mV, respectively, and the differences were statistically significant for all responses (for each, P< 0.05). Conclusion: ERG values are reasonably low in patients with Bietti's crystalline dystrophy when compared with normal values. ERG may be very useful in evaluation of visual prognosis and follow-up of these patients.