Parathyroid carcinoma is a rare malignancy and an infrequent cause of parathormone-dependent hypercalcemia. The most effective treatment for the tumor is a complete resection of the primary tumor. In spite of this, the tumor usually recurs. In the present study, we report the case of a 42-year-old patient who has undergone continuous ambulatory peritoneal dialysis and presented with hypercalcemia due to inoperable parathyroid carcinoma. The patient's hypercalcemia was successfully controlled with cinacalcet plus alendronate despite continuing parathyroid hormone overproduction.