Octylamine-oxalic acid (Oct-Oxa) deep eutectic solvent for the separation of Sudan II from food samples

SOYLAK M., Ahmed H. E. H., Konneh M.

Food Chemistry, cilt.464, 2025 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 464
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.foodchem.2024.141658
  • Dergi Adı: Food Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Chemical Abstracts Core, Chimica, Communication Abstracts, Compendex, EMBASE, Food Science & Technology Abstracts, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Anahtar Kelimeler: Sudan II dye, Deep eutectic solvents, Octylamine, Oxalic acid, Liquid-liquid microextraction (LLME), Food and water samples, UV-VIS spectrophotometry
  • Erciyes Üniversitesi Adresli: Evet

Özet

This work presents a novel deep eutectic solvent (DES) formed of octylamine and oxalic acid (Oct-Oxa) that was effectively used to separate Sudan II dye from food and water samples. The prepared DES was characterized using Fourier transform infrared spectroscopy (FT-IR) and carbon-13 nuclear magnetic resonance (13C NMR). Key parameters were optimized, including a short ultrasonication time of 30 s and a very low DES volume of only 500 μL that could be separated within one minute of centrifugation. The remaining parameters were also tested: pH (7), DES molar ratio (1:1), and sample volume (40 mL). The method demonstrates excellent recovery and accuracy, with limits of detection (LOD) of 1.2 μg kg−1 and quantification (LOQ) of 4.1 μg kg−1. It facilitates rapid separation and sensitive detection of Sudan II dye using ultraviolet-visible (UV-VIS) spectrophotometry. The novelty of this approach lies in the use of a novel DES, the minimal volume of DES required, and the efficiency of the short ultrasonication time, highlighting the method's potential for sustainable, cost-effective extraction in environmental and food safety applications.