Acromegaly is associated with decreased skin transepidermal water loss and temperature, and increased skin pH and sebum secretion partially reversible after treatment

BORLU M. , Karaca Z. C. , Yildiz H. , TANRIVERDİ F. , Demirel B., Elbuken G. , ...More

GROWTH HORMONE & IGF RESEARCH, vol.22, no.2, pp.82-86, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ghir.2012.02.006
  • Title of Journal : GROWTH HORMONE & IGF RESEARCH
  • Page Numbers: pp.82-86
  • Keywords: GH,IGF-1, Acromegaly, Treatment, Skin, Sebum, GROWTH-HORMONE DEFICIENCY, THERAPY, HYDRATION


Background: Acromegaly is characterized by an acquired progressive somatic disfigurement, mainly involving the face and extremities, besides many other organ involvement. Wet and oily skin was described in acromegaly patients and it was attributed to hyperhidrosis and increased sebum production but this suggestion has not been evaluated with reliable methods.