Relationship Between the Progression of Coronary Artery Disease and Pulse Pressure Index: A Cross-Sectional Work

Karadavut S., Kelesoglu S., Elcik D.

ANGIOLOGY, cilt.74, sa.7, ss.687-692, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 74 Sayı: 7
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1177/00033197221124765
  • Dergi Adı: ANGIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE
  • Sayfa Sayıları: ss.687-692
  • Anahtar Kelimeler: ambulatory blood pressure monitoring, coronary artery disease, pulse pressure, pulse pressure index, INTIMA-MEDIA THICKNESS, MYOCARDIAL-INFARCTION, CARDIOVASCULAR RISK, BLOOD-PRESSURE, ATHEROSCLEROSIS, HYPERTENSION, STIFFNESS
  • Erciyes Üniversitesi Adresli: Evet

Özet

This study sought to analyze the relationship between pulse pressure (PP) index (PPI) (PP/systolic blood pressure; a less variable and objective form of PP) and coronary artery disease (CAD) progression. A registry of 193 patients was evaluated to show CAD progression by comparing current vs previous (6 months to 3 years prior) angiograms. One day after the second angiogram, we conducted ambulatory blood pressure measurements on the patients. Of the 193 patients, 65 (34%) had CAD progression. The PP and PPI were significantly higher in the progression than in the non-progression group (55 +/- 12 vs. 51 +/- 10 mmHg, P = .02 and .47 +/- .06 vs. .42 +/- .05, P = .004, respectively). Also, the PP and PPI were independently predictive of CAD progression (OR = 1.03, P = .03 and OR = 6.47, P = .01, respectively). Moreover, the correlation of PPI with low-density lipoprotein cholesterol and glycosylated hemoglobin was greater than their correlation with PP. In addition, PPI predicted CAD progression better than PP (area under the curve [AUC] = .649 vs. .574, P = .03). Elevated PP and PPI may be associated with the progression of CAD. PPI seems more successful in predicting CAD progression than PP.