Relationship Between the Progression of Coronary Artery Disease and Pulse Pressure Index: A Cross-Sectional Work
ANGIOLOGY, vol.74, no.7, pp.687-692, 2023 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 74 Issue: 7
- Publication Date: 2023
- Doi Number: 10.1177/00033197221124765
- Journal Name: ANGIOLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE
- Page Numbers: pp.687-692
- Keywords: ambulatory blood pressure monitoring, coronary artery disease, pulse pressure, pulse pressure index
- Erciyes University Affiliated: Yes
Abstract
This study sought to analyze the relationship between pulse pressure (PP) index (PPI) (PP/systolic blood pressure; a less variable and objective form of PP) and coronary artery disease (CAD) progression. A registry of 193 patients was evaluated to show CAD progression by comparing current vs previous (6 months to 3 years prior) angiograms. One day after the second angiogram, we conducted ambulatory blood pressure measurements on the patients. Of the 193 patients, 65 (34%) had CAD progression. The PP and PPI were significantly higher in the progression than in the non-progression group (55 +/- 12 vs. 51 +/- 10 mmHg, P = .02 and .47 +/- .06 vs. .42 +/- .05, P = .004, respectively). Also, the PP and PPI were independently predictive of CAD progression (OR = 1.03, P = .03 and OR = 6.47, P = .01, respectively). Moreover, the correlation of PPI with low-density lipoprotein cholesterol and glycosylated hemoglobin was greater than their correlation with PP. In addition, PPI predicted CAD progression better than PP (area under the curve [AUC] = .649 vs. .574, P = .03). Elevated PP and PPI may be associated with the progression of CAD. PPI seems more successful in predicting CAD progression than PP.