5-Fluoro-N-(2-methyl-3-oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-3-phenyl-1H-indole-2-carboxamide


Celikesir S. T. , AKKURT M. , Ustundag G. C. , Buyukgungor O.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, cilt.69, 2013 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 69
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1107/s1600536813018576
  • Dergi Adı: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS

Özet

In the title compound, C24H24FN3O2S, the 1,3-thiazolidine ring adopts an envelope conformation with the S atom as the flap, while the cyclohexane ring is in a chair conformation. In the crystal, molecules are linked by N-H center dot center dot center dot O and C-H center dot center dot center dot F hydrogen bonds, forming a three-dimensional network. The unit cell contains six voids of 57 angstrom(3), but the residual electron density (highest peak = 0.23 e angstrom(-3) and deepest hole = -0.19 e angstrom(-3)) in the difference Fourier map suggests no solvent molecule occupies this void.