Recurrent Sarcoidosis Presenting With Bilateral Leg Edema: A Case Report


Draves J., TEKİNER H., Yale S. H., Yale E. S.

JOURNAL OF CLINICAL PRACTICE AND RESEARCH, cilt.48, sa.5, ss.576-579, 2026 (ESCI, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 5
  • Basım Tarihi: 2026
  • Doi Numarası: 10.14744/cpr.2026.82224
  • Dergi Adı: JOURNAL OF CLINICAL PRACTICE AND RESEARCH
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM), Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
  • Sayfa Sayıları: ss.576-579
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: Bilateral lower extremity edema may serve as an early clinical manifestation of pulmonary sarcoidosis. Identifying sarcoidosis as the underlying cause can be challenging in patients with or without a prior history of the disease, as lower extremity edema is not typically considered part of its clinical spectrum. Case Report: A 63-year-old man presented with a complex medical history, including non-Hodgkin lymphoma, bilateral renal cell carcinoma, colon cancer, and pleomorphic sarcoma of the upper extremity. He also had a history of recurrent pulmonary sarcoidosis. He reported a 6-month history of bilateral pitting lower extremity edema that developed several months before the onset of dyspnea. Conclusion: In patients with multiple comorbidities, recognizing sarcoidosis as a potential cause of bilateral lower extremity edema requires careful exclusion of systemic and malignant etiologies. Sarcoidosis should be considered when more common causes have been excluded.