JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.27, ss.175-179, 2014 (SCI-Expanded)
Abstract
Background: Isolated premature thelarche is the breast
development in the absence of other secondary sex characteristics
in prepubertal girls. Fennel is a plant which
contains a phytoestrogen called anethole as an active
ingredient.
Case: Here, we report a case of a 12-month-old girl who
showed breast development that became apparent in the
last 3 months. Her medical history revealed that she was
given two to three teaspoons of fennel tea by her mother
every day for restlessness for the last 6 months. Isolated
premature thelarche was diagnosed based on physical
and laboratory findings. On follow-up, after cessation
of fennel consumption, the breast development of the
patient regressed gradually and became normal by the
end of 1 year.
Conclusion: Reporting this case, we want to emphasize
the importance of awareness of fennel tea, a commonly
used plant in babies, as a preventable cause of premature
thelarche.
Keywords: fennel tea; isolated premature thelarche;
phytoestrogen.
*Corresponding author: Deniz Okdemir, Faculty of Medicine,