Eugene Hertoghe (1860-1928): Pioneer in endocrinology and the treatment of hypothyroidism

TEKİNER H., Yale E. S., Yale S. H.

JOURNAL OF MEDICAL BIOGRAPHY, 2025 (AHCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1177/09677720241307877
  • Dergi Adı: JOURNAL OF MEDICAL BIOGRAPHY
  • Derginin Tarandığı İndeksler: Arts and Humanities Citation Index (AHCI), Scopus, American History and Life, Historical Abstracts, MEDLINE
  • Anahtar Kelimeler: Endocrinology, eponym, history of medicine, hypothyroidism, Hertoghe sign
  • Erciyes Üniversitesi Adresli: Evet

Özet

Eug & egrave;ne Hertoghe (1860-1928), a Belgian internist and former vice-president of the Royal Academy of Medicine of Belgium, made significant contributions to the understanding and treatment of chronic hypothyroidism. He provided a detailed clinical description of the condition, emphasizing its multisystemic manifestations and hereditary aspects. Hertoghe also documented the therapeutic use of thyroid extract, reporting its effectiveness in alleviating symptoms of hypothyroidism. Among his contributions, he described the "Hertoghe sign," a rare clinical feature characterized by the loss of the outer third of the eyebrows, commonly associated with myxoedema, as well as with cases of toxic poisoning, infections, and atopic dermatitis.