KUWAIT JOURNAL OF SCIENCE & ENGINEERING, cilt.29, sa.2, ss.57-65, 2002 (SCI-Expanded)
In this study, reactions similar to the Michael-type nucleophilic cycloaddition of the 4-panisoyl-5-p-anisyl-2,3-furandione (1) with monosubstituted ureas and thioureas 2a-g gave N-alkyl pyrimidine derivatives 3a-g, with loss of carbon dioxide and water. These new heterocyclic compounds 3a-g were obtained in moderate to excellent yields 40-96%. The compound 1 was easily prepared by the reaction of dianisoylmethane with oxalyl dichloride. First the compounds 3 were synthesized, the results obtained were then interpreted. The structures of the compounds 3a-g were determined by the H-1 NMR, IR spectroscopy and elemental analyses.