Is TNF-alpha gene polymorphism related to pulmonary functions and prognosis as determined by FEV1, BMI, COPD exacerbation and hospitalization in patients with smoking-related COPD in a Turkish population?

Ozdogan N., TUTAR N., Demir R., SAATÇİ Ç., Kanbay A., Buyukoglan H.

REVISTA PORTUGUESA DE PNEUMOLOGIA, cilt.20, sa.6, ss.305-310, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.rppneu.2014.03.003
  • Dergi Adı: REVISTA PORTUGUESA DE PNEUMOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.305-310
  • Erciyes Üniversitesi Adresli: Evet

Özet

Introduction: Some conflicting results have been published about the relationship between TNF-alpha-308 gene polymorphism and chronic obstructive pulmonary disease (COPD). The aim of this study was to determine whether TNF-alpha-308 gene polymorphism was associated with smoking-related COPD and whether it was associated with pulmonary function parameters (PFTs), body mass index (BMI), and prognosis.