Is TNF-alpha gene polymorphism related to pulmonary functions and prognosis as determined by FEV1, BMI, COPD exacerbation and hospitalization in patients with smoking-related COPD in a Turkish population?


Ozdogan N. , TUTAR N. , Demir R. , SAATÇİ Ç. , Kanbay A. , Buyukoglan H.

REVISTA PORTUGUESA DE PNEUMOLOGIA, cilt.20, ss.305-310, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20 Konu: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.rppneu.2014.03.003
  • Dergi Adı: REVISTA PORTUGUESA DE PNEUMOLOGIA
  • Sayfa Sayısı: ss.305-310

Özet

Introduction: Some conflicting results have been published about the relationship between TNF-alpha-308 gene polymorphism and chronic obstructive pulmonary disease (COPD). The aim of this study was to determine whether TNF-alpha-308 gene polymorphism was associated with smoking-related COPD and whether it was associated with pulmonary function parameters (PFTs), body mass index (BMI), and prognosis.