A preliminary study of the genes related to aggression and insensitivity to pain in autism spectrum disorders

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ŞENER E. F., ŞAHİN M. C., TAHERİ S., BAYRAMOV K. K., MARAŞLI M. K., ZARARSIZ G., ...More

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, vol.27, no.1, pp.24-29, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 1
  • Publication Date: 2017
  • Doi Number: 10.1080/24750573.2017.1293248
  • Journal Name: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.24-29
  • Keywords: Autism spectrum disorders, aggression, insensitivity to pain, expression, CHALLENGING BEHAVIOR, EMOTIONAL-PROBLEMS, CHILDREN, RECEPTOR, SEROTONIN, ASSOCIATION, PREVALENCE, GENETICS, RISK
  • Erciyes University Affiliated: Yes

Abstract

Objective: Autism spectrum disorders (ASDs) is a heterogeneous neuropsychiatric disorder with widespread abnormalities of social interaction and communication, showing severely restricted interests and extreme repetitive behavior. The relationship between aggressive behavior, insensitivity to pain, and ASDs could not be explained completely. Therefore, we aimed to contribute to the etiology by examining the gene expressions of OPRL1, TACR1, and HTR1E in patients with ASDs.