European Biotechnology Congress 2015, Bucuresti, Romanya, 7 - 09 Mayıs 2015, cilt.208, ss.23-24
The
differentiation of intracranial hemorrhage and calcification on conventional MR
images is often challenging. Both pathologies show varying signal intensities
on T1- and T2-weighted images. Thus, Computed Tomography is often required in
confirmation of calcification.
Phase
information in Susceptibility Weighted Imaging can provide contrast in
differentiation of two pathologies. Recently, Quantitative Susceptibility
Mapping (QSM) has been shown to be useful in this separation since QSM provides
a map of local tissue magnetic susceptibility by utilizing both magnitude and
phase data and performing a dipole deconvolution.
In
this study, we explored efficiency of QSM in identification of intracranial
calcifications and hemorrhages on seven different cases (six hemorrhage cases
with several lesions and one calcification case with both calcification and
hemorrhage) and compared its findings with the detection using SWI phase data.
SWI
phase images showed seventeen out of nineteen hemorrhage lesions but failed to
identify almost any lesions whether it’s a hemorrhage or calcification while eighteen
out of nineteen hemorrhage lesions were identified on QSM images. Similarly,
the calcified lesion was identified on QSM images but not on SWI phase images. Based
on our results, we conclude that QSM provides great utility in identification
of hemorrhage and calcification.