Increased sister chromatid exchanges in workers exposed to occupational lead and zinc

Donmez H., Dursun N., Ozkul Y., Demirtas H.

BIOLOGICAL TRACE ELEMENT RESEARCH, cilt.61, sa.1, ss.105-109, 1998 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 1
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1007/bf02784046
  • Dergi Adı: BIOLOGICAL TRACE ELEMENT RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.105-109
  • Anahtar Kelimeler: lead, zinc, sister chromatid exchange, CHROMOSOMAL-ABERRATIONS, GENOTOXICITY, CELLS
  • Erciyes Üniversitesi Adresli: Evet

Özet

Sister chromatid exchange (SCE) in blood lymphocytes was determined in 32 male workers occupationally exposed to lead (Pb) and zinc (Zn) and in 20 controls matched for age and smoking habits. Exposed workers have higher SCE mean values than control workers (p < 0.01). In exposed persons, blood Pb concentrations were also significantly higher than controls (p < 0.0001), but the difference between Zn levels in the blood of these groups was not found to be significant (p > 0.05). Our results indicate that Pb may be genotoxic and harmful to human health.