Non-Infectious Diseases Compatible With COVID-19 Pneumonia


BARAN KETENCİOĞLU B., YİĞİT F., Almadqa M., TUTAR N., YILMAZ İ.

CUREUS, cilt.12, sa.8, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12 Sayı: 8
  • Basım Tarihi: 2020
  • Doi Numarası: 10.7759/cureus.9989
  • Dergi Adı: CUREUS
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Directory of Open Access Journals
  • Anahtar Kelimeler: coronavirus disease 2019 (covid-19), rt-pcr (real time - reverse transcription polymerase chain reaction), ct (computed tomography) imaging, peripheral eosinophilia
  • Erciyes Üniversitesi Adresli: Evet

Özet

While the definitive diagnosis of the coronavirus disease 19 (COVID-19) is mainly made by the polymerase chain reaction (PCR), some PCR-negative cases are diagnosed typically by a computed tomography (CT) scan's radiology. However, there are many different infectious and non-infectious diseases that have radiology like COVID-19. We are presenting a case of a patient having symptoms and a CT scan radiology comparable to that of COVID-19 and also having eosinophilia. The patient was initially diagnosed and treated as a COVID-19 patient. The patient stated that she had always complained of having dyspnea and cough, but it had increased even more in the past few days. Her thorax CT revealed bilateral ground-glass opacities with upper lobe predominance, which was reported as highly compatible with COVID-19 by radiologists. COVID-19 PCR result was negative twice. In laboratory results, eosinophil count was 2,850/mm(3) and total Ig was 768 IU/mL. However, when the laboratory values and the radiological findings were combined with the patient's history, COVID-19 was excluded and the chronic eosinophilic pneumonia was accepted as a diagnosis. Clinicians more focused on COVID-19 while questioning the patients and while evaluating the laboratory and the radiological findings make it easier to miss other infectious and non-infectious diseases. Assessing the complete blood count result, focusing on the lymphocyte value, also makes it easy to skip eosinophilia.