Renal tubular dysgenesis with atypical histology and in-utero exposure to naproxen sodium

Koklu E., GURGOZE M., Akgun H., Ozturk M. A., POYRAZOGLU M. H.

ANNALS OF TROPICAL PAEDIATRICS, cilt.26, sa.3, ss.241-245, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1179/146532806x120345
  • Dergi Adı: ANNALS OF TROPICAL PAEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.241-245
  • Erciyes Üniversitesi Adresli: Evet

Özet

Renal tubular dysgenesis (RTD), a rare, lethal, autosomal recessive disorder, is characterised by short and poorly differentiated proximal convoluted tubules associated with oligohydramnios, Potter sequence and neonatal death from respiratory failure. We report an unusual case of neonatal anuria owing to RTD with normally formed lungs, in-utero exposure to naproxen sodium and atypical histology in that the glomeruli were not as crowded as usually seen in RTD. When there is anuria in an infant following birth in the context of a normal renal ultrasound and an absence of objective evidence of perinatal hypoxia, RTD should be considered.