Signet ring-like cells in pituitary adenoma


DENİZ K. , TANRIVERDİ F. , SELÇUKLU A. , KONTAŞ O. , Kelestimur F.

PATHOLOGY RESEARCH AND PRACTICE, cilt.204, ss.209-212, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 204 Konu: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.prp.2007.11.008
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Sayfa Sayıları: ss.209-212

Özet

We describe a case of non-functioning pituitary adenoma in a 35-year-old woman with a prior history of fertility problems. The patient had received clomiphen citrate and human chorionic gonadotrophin for 3 years. Histological examination of the tumor revealed signet ring-like cell areas admixed with minor conventional round-polygonal neoplastic cells. The two populations of tumor cells showed strong immunoreactivity for chromogranin and synaptophysin.