Signet ring-like cells in pituitary adenoma

DENİZ K., TANRIVERDİ F., SELÇUKLU A., KONTAŞ O., Kelestimur F.

PATHOLOGY RESEARCH AND PRACTICE, cilt.204, sa.3, ss.209-212, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 204 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.prp.2007.11.008
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.209-212
  • Erciyes Üniversitesi Adresli: Evet

Özet

We describe a case of non-functioning pituitary adenoma in a 35-year-old woman with a prior history of fertility problems. The patient had received clomiphen citrate and human chorionic gonadotrophin for 3 years. Histological examination of the tumor revealed signet ring-like cell areas admixed with minor conventional round-polygonal neoplastic cells. The two populations of tumor cells showed strong immunoreactivity for chromogranin and synaptophysin.