Signet ring-like cells in pituitary adenoma

DENİZ K., TANRIVERDİ F., SELÇUKLU A., KONTAŞ O., Kelestimur F.

PATHOLOGY RESEARCH AND PRACTICE, vol.204, no.3, pp.209-212, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 204 Issue: 3
  • Publication Date: 2008
  • Doi Number: 10.1016/j.prp.2007.11.008
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.209-212
  • Erciyes University Affiliated: Yes

Abstract

We describe a case of non-functioning pituitary adenoma in a 35-year-old woman with a prior history of fertility problems. The patient had received clomiphen citrate and human chorionic gonadotrophin for 3 years. Histological examination of the tumor revealed signet ring-like cell areas admixed with minor conventional round-polygonal neoplastic cells. The two populations of tumor cells showed strong immunoreactivity for chromogranin and synaptophysin.