Investigating the mRNA expression of IL-8 in Response to Lipopolysaccharide (LPS) and Lipoteichoic Acid (LTA) Stimulation in Sheep Alveolar Macrophages

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Sohel M. M. H., Çinar M. U.

11th INTERNATIONAL ANIMAL SCIENCE CONGRESS, Kayseri, Türkiye, 20 - 22 Ekim 2019, ss.79-80, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Kayseri
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.79-80
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Erciyes Üniversitesi Adresli: Evet

Özet

The immune system of an organism is the most important defense system against harmful pathogens and this system is tightly regulated by the timely expression of several genes. Interleukin-8 (IL-8) is a chemoattractant cytokine produced by a variety of tissue and blood cells. It has a distinct target specificity for the neutrophil cells. IL-8 attracts and activates neutrophils in inflammatory regions. The aim of present study was to investigate the dynamics of expression of IL-8 in response to LPS and LTA in different time points which could later be used to select sheep against respiratory diseases effectively (Janette and Etheresia, 2016)