Comparison of the Effects of Ketamine or Lidocaine on Fentanyl-Induced Cough in Patients Undergoing Surgery: A Prospective, Double-Blind, Randomized, Placebo-Controlled Study

GÜLER, GÜLEN; AKSU, RECEP; BİÇER, CİHANGİR; TOSUN, ZEYNEP; BOYACI, Adem

doi:10.1016/j.curtheres.2010.10.004

Comparison of the Effects of Ketamine or Lidocaine on Fentanyl-Induced Cough in Patients Undergoing Surgery: A Prospective, Double-Blind, Randomized, Placebo-Controlled Study

GÜLER G., AKSU R., BİÇER C., TOSUN Z., BOYACI A.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.71, sa.5, ss.289-297, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 71 Sayı: 5
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.curtheres.2010.10.004
Dergi Adı: CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.289-297
Anahtar Kelimeler: fentanyl, coughing, ketamine, lidocaine
Erciyes Üniversitesi Adresli: Evet

Özet

BACKGROUND: Fentanyl-induced cough is common but has not been viewed as a serious anesthetic problem. However, the cough may be explosive at times, may require immediate intervention, and may be associated with undesirable increases in intracranial, intraocular, and intra-abdominal pressures. Prevention of fentanyl-induced cough in such situations is of paramount importance. Ketamine, at concentrations achieved with standard clinical doses, has a direct relaxant effect on airway smooth muscle.