Comparison of the Effects of Ketamine or Lidocaine on Fentanyl-Induced Cough in Patients Undergoing Surgery: A Prospective, Double-Blind, Randomized, Placebo-Controlled Study


GÜLER G., AKSU R., BİÇER C., TOSUN Z., BOYACI A.

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, cilt.71, sa.5, ss.289-297, 2010 (SCI-Expanded) identifier identifier identifier

Özet

BACKGROUND: Fentanyl-induced cough is common but has not been viewed as a serious anesthetic problem. However, the cough may be explosive at times, may require immediate intervention, and may be associated with undesirable increases in intracranial, intraocular, and intra-abdominal pressures. Prevention of fentanyl-induced cough in such situations is of paramount importance. Ketamine, at concentrations achieved with standard clinical doses, has a direct relaxant effect on airway smooth muscle.