The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint


Cevik O. , GERGIN O. O. , YILDIZ K. , BAYRAM A. , CANÖZ Ö. , HALICI M. , et al.

REVISTA BRASILEIRA DE ANESTESIOLOGIA, cilt.68, ss.605-612, 2018 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 68 Konu: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.bjan.2018.06.013
  • Dergi Adı: REVISTA BRASILEIRA DE ANESTESIOLOGIA
  • Sayfa Sayısı: ss.605-612

Özet

Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.