The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint

Cevik, Osman; Gergın, ÖZLEM; Yıldız, KARAMEHMET; Bayram , ADNAN; Canöz, ÖZLEM; Halıcı, MEHMET; Baran, MÜNEVVER; Yay, ARZU; Polat, Sait

doi:10.1016/j.bjan.2018.06.013

The chondrotoxic and apoptotic effects of levobupivacaine and bupivacaine on the rabbit knee joint

Cevik O., Gergın O. O., Yıldız K., Bayram A., Canöz Ö., Halıcı M., ...Daha Fazla

REVISTA BRASILEIRA DE ANESTESIOLOGIA, cilt.68, ss.605-612, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 68
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.bjan.2018.06.013
Dergi Adı: REVISTA BRASILEIRA DE ANESTESIOLOGIA
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.605-612
Anahtar Kelimeler: Apoptosis, Bupivacaine, Chondrotoxicity, Levobupivacaine, Local anesthetic
Erciyes Üniversitesi Adresli: Evet

Özet

Background: A single dose injection or continuous infusion of local anesthetics into the joint space is considered to be a well-defined analgesia technique. The aim of this study was to investigate the chondrotoxic and apoptotic effects of single-dose intra-articular injection of levobupivacaine and bupivacaine on rabbit knee joint tissues.