Akademik Veri Yönetim Sistemi
Microchemical Journal, cilt.216, 2025 (SCI-Expanded, Scopus)
In this study, a novel dispersive microsolid phase extraction (dμSPE) method was developed for the enrichment and determination of di-2-ethylhexyl phthalate (DEHP), a widely used plasticizer and known endocrine disruptor. The innovation of this work lies in the direct application of pure MOF-5@ZnO nanocomposite, without any additional functionalization or metal doping, as an efficient sorbent for phthalate extraction. This marks the first demonstration of MOF-5@ZnO's superior performance in extracting DEHP from complex aqueous matrices. The nanocomposite was synthesized and characterized using Fourier-transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), and field emission scanning electron microscopy (FESEM). Key extraction parameters, including sorbent amount, eluent type and volume, pH, salt concentration, and sample volume, were optimized using a model solution. Optimal conditions were determined as 15 mg of MOF-5@ZnO and elution with 0.5 mL methanol: acetonitrile (1:1 v/v) from a 10 mL sample. The method demonstrated a limit of detection (LOD) of 2.6 ng mL−1 and a limit of quantification (LOQ) of 8.7 ng mL−1, with an enrichment factor up to 100 and recovery rates exceeding 90 %. Calibration showed excellent linearity (R2 = 0.9993). The method was successfully applied to various real samples, including tap water, mineral water, seawater, and industrial wastewater. Accuracy was confirmed via standard addition, with recoveries consistently above 90 %. Adsorption studies indicated a maximum adsorption capacity of 16.26 mg g−1 and followed the Langmuir isotherm model, suggesting monolayer adsorption. The developed method offers a sensitive and reliable approach for monitoring DEHP in environmental and food matrices.